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Department of
Anesthesiology

Provides services for over 50,000 anesthetics annually in 46 anesthetic sites, primarily at University of Cincinnati Medical Center.

Photo of Arthur d. Prudente

Peer Reviewed Publications

da Silva, Ana Merian; de Amorim Ferreira, Marcella; Schran, Roberta Giusti; Lückemeyer, Debora Denardin; Prudente, Arthur Silveira; Ferreira, Juliano 2025. Investigation of the participation of the TRPV1 receptor in the irritant effect of dithranol in mice. European journal of pharmacology, 994 , 177291

Lee, Sang Hoon; Tonello, Raquel; Lee, Kihwan; Roh, Jueun; Prudente, Arthur Silveira; Kim, Yong Ho; Park, Chul-Kyu; Berta, Temugin 2025. The Parkinson's disease DJ-1/PARK7 gene controls peripheral neuronal excitability and painful neuropathy. Brain : a journal of neurology, 148 5, 1639-1651

Xie, Wenrui; Lückemeyer, Debora Denardin; Qualls, Katherine A; Prudente, Arthur Silveira; Berta, Temugin; Gu, Mingxia; Strong, Judith A; Dong, Xinzhong; Zhang, Jun-Ming 2025. Vascular motion in the dorsal root ganglion sensed by Piezo2 in sensory neurons triggers episodic pain. Neuron, 113 11, 1774-1788.e5

Lee, Sang Hoon; Bonifacio, Fabio; Prudente, Arthur Silveira; Choi, Y I; Roh, Jueun; Adjafre, Beatriz Lima; Park, Chul-Kyu; Jung, Sung Jun; Cunha, Thiago M; Berta, Temugin 2024. STING recognition of viral dsDNA by nociceptors mediates pain in mice. Brain, behavior, and immunity, 121 , 29-42

Li, Xinmeng; Prudente, Arthur Silveira; Prato, Vincenzo; Guo, Xianchuan; Hao, Han; Jones, Frederick; Figoli, Sofia; Mullen, Pierce; Wang, Yujin; Tonello, Raquel; Lee, Sang Hoon; Shah, Shihab; Maffei, Benito; Berta, Temugin; Du, Xiaona; Gamper, Nikita 2024. Peripheral gating of mechanosensation by glial diazepam binding inhibitor. The Journal of clinical investigation, 134 16,

Li, Xinmeng; Prudente, Arthur Silveira; Prato, Vincenzo; Guo, Xianchuan; Hao, Han; Jones, Frederick; Figoli, Sofia; Mullen, Pierce; Wang, Yujin; Tonnello, Raquel; Lee, Sang Hoon; Shah, Shihab; Maffei, Benito; Berta, Temugin; Du, Xiaona; Gamper, Nikita 2023. Peripheral gating of pain by glial endozepine. bioRxiv : the preprint server for biology, ,

Lückemeyer, Debora Denardin; Prudente, Arthur Silveira; de Amorim Ferreira, Marcella; da Silva, Ana Merian; Tonello, Raquel; Junior, Sérgio José Macedo; do Prado, Camila Sant' Helena; de Castro Júnior, Célio José; Gomez, Marcus Vinicius; Calixto, João Batista; Ferreira, Juliano 2023. Critical Pronociceptive Role of Family 2 Voltage-Gated Calcium Channels in a Novel Mouse Model of HIV-Associated Sensory Neuropathy. Molecular neurobiology, 60 5, 2954-2968

Lückemeyer, Debora Denardin; Xie, Wenrui; Prudente, Arthur Silveira; Qualls, Katherine A; Tonello, Raquel; Strong, Judith A; Berta, Temugin; Zhang, Jun-Ming 2023. The Antinociceptive Effect of Sympathetic Block is Mediated by Transforming Growth Factor β in a Mouse Model of Radiculopathy. Neuroscience bulletin, 39 9, 1363-1374

Cohen, Cinder Faith; Prudente, Arthur Silveira; Berta, Temugin; Lee, Sang Hoon 2021. Transient Receptor Potential Channel 4 Small-Molecule Inhibition Alleviates Migraine-Like Behavior in Mice. Frontiers in molecular neuroscience, 14 , 765181

Ferreira, Marcella Amorim; Lückemeyer, Débora Denardin; Macedo-Júnior, Sérgio José; Schran, Roberta Giusti; Silva, Ana Merian; Prudente, Arthur Silveira; Tonello, Raquel; Ferreira, Juliano 2021. Sex-dependent Cav2.3 channel contribution to the secondary hyperalgesia in a mice model of central sensitization. Brain research, 1764 , 147438

Norões, Maíra Macedo; Santos, Larissa Gonzaga; Gavioli, Elaine Cristina; de Paula Soares Rachetti, Vanessa; Otuki, Michel Fleith; de Almeida Cabrini, Daniela; da Silveira Prudente, Arthur; Oliveira, Janiana Raíza Jentsch Matias; de Carvalho Gonçalves, Muryel; Ferreira, Juliano; Preti, Delia; De Logu, Francesco; Nassini, Romina; André, Eunice 2019. Role of TRPA1 receptors in skin inflammation induced by volatile chemical irritants in mice. European journal of pharmacology, 858 , 172460

Prestes, Ana Paula; Machado, Willian Moreira; Oliveira, Junior Garcia; Olchanheski, Luiz Renato; Santos, Fábio André; Alves, Gustavo Ferreira; Prudente, Arthur Silveira; Otuki, Michel Fleith; Paludo, Kátia Sabrina; Sordi, Regina; Fernandes, Daniel 2018. Experimental periodontitis in rats potentiates inflammation at a distant site: Role of B1 kinin receptor. Life sciences, 194 , 40-48

Gonçalves, Muryel Carvalho; Horewicz, Verônica Vargas; Lückemeyer, Débora Denardin; Prudente, Arthur Silveira; Assreuy, Jamil 2017. Experimental Sepsis Severity Score Associated to Mortality and Bacterial Spreading is Related to Bacterial Load and Inflammatory Profile of Different Tissues. Inflammation, 40 5, 1553-1565

Prudente, Arthur S; Sponchiado, Graziela; Mendes, Daniel A G B; Soley, Bruna S; Cabrini, Daniela A; Otuki, Michel F 2017. Pre-clinical efficacy assessment of Malva sylvestris on chronic skin inflammation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 93 , 852-860

Campos, Patrícia Mazureki; Prudente, Arthur Silveira; Horinouchi, Cíntia Delai da Silva; Cechinel-Filho, Valdir; Fávero, Giovani Marino; Cabrini, Daniela Almeida; Otuki, Michel Fleith 2015. Inhibitory effect of GB-2a (I3-naringenin-II8-eriodictyol) on melanogenesis. Journal of ethnopharmacology, 174 , 224-9

Borsato, Débora M; Prudente, Arthur S; Döll-Boscardin, Patrícia M; Borsato, Aurélio V; Luz, Cynthia F P; Maia, Beatriz H L N S; Cabrini, Daniela A; Otuki, Michel F; Miguel, Marilis D; Farago, Paulo V; Miguel, Obdulio G 2014. Topical anti-inflammatory activity of a monofloral honey of Mimosa scabrella provided by Melipona marginata during winter in southern Brazil. Journal of medicinal food, 17 7, 817-25

Oliveira, Sara Marchesan; Silva, Cássia Regina; Wentz, Alexandre Pereira; Paim, Gisele R; Correa, Michele S; Bonacorso, Hélio G; Prudente, Arthur S; Otuki, Michel Fleith; Ferreira, Juliano 2014. Antinociceptive effect of 3-(4-fluorophenyl)-5-trifluoromethyl-1H-1-tosylpyrazole. A Celecoxib structural analog in models of pathological pain. Pharmacology, biochemistry, and behavior, 124 , 396-404

Prudente, Arthur S; Loddi, Alliete M V; Duarte, Márcia R; Santos, Adair R S; Pochapski, Marcia T; Pizzolatti, Moacir G; Hayashi, Sirlei S; Campos, Francinete R; Pontarolo, Roberto; Santos, Fabio A; Cabrini, Daniela A; Otuki, Michel F 2013. Pre-clinical anti-inflammatory aspects of a cuisine and medicinal millennial herb: Malva sylvestris L. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 58 , 324-31

Cabrini, Daniela Almeida; Moresco, Henrique Hunger; Imazu, Priscila; da Silva, Cíntia Delai; Pietrovski, Evelise Fernandes; Mendes, Daniel Augusto Gasparin Bueno; da Silveira Prudente, Arthur; Pizzolatti, Moacir Geraldo; Brighente, Inês Maria Costa; Otuki, Michel Fleith 2011. Analysis of the Potential Topical Anti-Inflammatory Activity of Averrhoa carambola L. in Mice. Evidence-based complementary and alternative medicine : eCAM, 2011 , 908059

Otuki, M F; Reis, R C; Cabrini, D; Prudente, A S; Horinouchi, C D S; Correr, C J 2011. Patient-reported outcomes in psoriasis research and practice. The British journal of dermatology, 165 6, 1361-2

Otuki, Michel F; Bernardi, Camila A; Prudente, Arthur S; Laskoski, Kerly; Gomig, Franciane; Horinouchi, Cintia D S; Guimarães, Claudio L; Ferreira, Juliano; Delle-Monache, Franco; Cechinel-Filho, Valdir; Cabrini, Daniela A 2011. Garcinia gardneriana (Planchon & Triana) Zappi. (Clusiaceae) as a topical anti-inflammatory alternative for cutaneous inflammation. Basic & clinical pharmacology & toxicology, 109 1, 56-62

Silva, Cássia Regina; Oliveira, Sara Marchesan; Rossato, Mateus Fortes; Dalmolin, Gerusa Duarte; Guerra, Gustavo Petri; da Silveira Prudente, Arthur; Cabrini, Daniela Almeida; Otuki, Michel Fleith; André, Eunice; Ferreira, Juliano 2011. The involvement of TRPA1 channel activation in the inflammatory response evoked by topical application of cinnamaldehyde to mice. Life sciences, 88 25-26, 1077-87

Castardo, Jaqueline C; Prudente, Arthur S; Ferreira, Juliano; Guimarães, Cláudio L; Monache, Franco Delle; Filho, Valdir Cechinel; Otuki, Michel F; Cabrini, Daniela A 2008. Anti-inflammatory effects of hydroalcoholic extract and two biflavonoids from Garcinia gardneriana leaves in mouse paw oedema. Journal of ethnopharmacology, 118 3, 405-11

Otuki M.F.; Schwob O.; Silveira Prudente A.; Zaltsman I.; Meretski S.; Segal J.; Yedgar S.; Rosenblat G. 12-15-2011. Attenuation of experimental TPA-induced dermatitis by acetylenic acetogenins is associated with inhi European Journal of Pharmacology, 672 1-3, 175-179

Otuki M.F.; Schwob O.; Silveira Prudente A.; Zaltsman I.; Meretski S.; Segal J.; Yedgar S.; Rosenblat G. 12-15-2011. Attenuation of experimental TPA-induced dermatitis by acetylenic acetogenins is associated with inhi European Journal of Pharmacology, 672 1-3, 175-179

Mendes D.; Soley B.; Prudente A.; Sponchiado G.; Ferreira B.; dos Santos M.; de Andrade A.; Amorim C.; Bresolin T.; Meyre-Silva C.; Zuffellato-Ribas K.; Assreuy J.; Otuki M.; Cabrini D. 12-01-2016. Hydroalcoholic extract of Sapium glandulatum (Vell.) Pax displays potent anti-inflammatory activitie Phytomedicine, 23 13, 1610-1620

Mendes D.; Soley B.; Prudente A.; Sponchiado G.; Ferreira B.; dos Santos M.; de Andrade A.; Amorim C.; Bresolin T.; Meyre-Silva C.; Zuffellato-Ribas K.; Assreuy J.; Otuki M.; Cabrini D. 12-01-2016. Hydroalcoholic extract of Sapium glandulatum (Vell.) Pax displays potent anti-inflammatory activitie Phytomedicine, 23 13, 1610-1620

Cohen C.F.; Prudente A.S.; Berta T.; Lee S.H. 11-01-2021. Transient Receptor Potential Channel 4 Small-Molecule Inhibition Alleviates Migraine-Like Behavior i Frontiers in Molecular Neuroscience, 14 ,

Cohen C.F.; Prudente A.S.; Berta T.; Lee S.H. 11-01-2021. Transient Receptor Potential Channel 4 Small-Molecule Inhibition Alleviates Migraine-Like Behavior i Frontiers in Molecular Neuroscience, 14 ,

Tonello R.; Silveira Prudente A.; Hoon Lee S.; Faith Cohen C.; Xie W.; Paranjpe A.; Roh J.; Park C.K.; Chung G.; Strong J.A.; Zhang J.M.; Berta T. 10-01-2023. Single-cell analysis of dorsal root ganglia reveals metalloproteinase signaling in satellite glial c Brain Behavior and Immunity, 113 , 401-414

Tonello R.; Silveira Prudente A.; Hoon Lee S.; Faith Cohen C.; Xie W.; Paranjpe A.; Roh J.; Park C.K.; Chung G.; Strong J.A.; Zhang J.M.; Berta T. 10-01-2023. Single-cell analysis of dorsal root ganglia reveals metalloproteinase signaling in satellite glial c Brain Behavior and Immunity, 113 , 401-414

Mendes D.; Horinouchi C.; Prudente A.; Soley B.; Assreuy J.; Otuki M.; Cabrini D. 07-15-2012. In vivo participation of nitric oxide in hyperproliferative epidermal phenomena in mice European Journal of Pharmacology, 687 1-3, 1-8

Mendes D.; Horinouchi C.; Prudente A.; Soley B.; Assreuy J.; Otuki M.; Cabrini D. 07-15-2012. In vivo participation of nitric oxide in hyperproliferative epidermal phenomena in mice European Journal of Pharmacology, 687 1-3, 1-8

Otuki M.; Cabrini D.; Moresco H.; Imazu P.; Silva C.; Pietrovski E.; Mendes D.; Prudente A.; Pizzolatti M.; Brighente I. 06-22-2011. Analysis of the potential topical anti-inflammatory activity of Averrhoa carambola L. in mice Evidence Based Complementary and Alternative Medicine, 2011 ,

Otuki M.; Cabrini D.; Moresco H.; Imazu P.; Silva C.; Pietrovski E.; Mendes D.; Prudente A.; Pizzolatti M.; Brighente I. 06-22-2011. Analysis of the potential topical anti-inflammatory activity of Averrhoa carambola L. in mice Evidence Based Complementary and Alternative Medicine, 2011 ,

Campos P.; Horinouchi C.; Prudente A.; Cechinel-Filho V.; Cabrini D.; Otuki M. 06-21-2013. Effect of a Garcinia gardneriana (Planchon and Triana) Zappi hydroalcoholic extract on melanogenesis Journal of Ethnopharmacology, 148 1, 199-204

Campos P.; Horinouchi C.; Prudente A.; Cechinel-Filho V.; Cabrini D.; Otuki M. 06-21-2013. Effect of a Garcinia gardneriana (Planchon and Triana) Zappi hydroalcoholic extract on melanogenesis Journal of Ethnopharmacology, 148 1, 199-204

Adami M.; Prudente A.; Mendes D.; Horinouchi C.; Cabrini D.; Otuki M. 05-01-2012. Simvastatin ointment, a new treatment for skin inflammatory conditions Journal of Dermatological Science, 66 2, 127-135

Adami M.; Prudente A.; Mendes D.; Horinouchi C.; Cabrini D.; Otuki M. 05-01-2012. Simvastatin ointment, a new treatment for skin inflammatory conditions Journal of Dermatological Science, 66 2, 127-135

Silveira Prudente A.; Hoon Lee S.; Roh J.; Luckemeyer D.D.; Cohen C.F.; Pertin M.; Park C.K.; Suter M.R.; Decosterd I.; Zhang J.M.; Ji R.R.; Berta T. 03-01-2024. Microglial STING activation alleviates nerve injury-induced neuropathic pain in male but not female Brain Behavior and Immunity, 117 , 51-65

Silveira Prudente A.; Hoon Lee S.; Roh J.; Luckemeyer D.D.; Cohen C.F.; Pertin M.; Park C.K.; Suter M.R.; Decosterd I.; Zhang J.M.; Ji R.R.; Berta T. 03-01-2024. Microglial STING activation alleviates nerve injury-induced neuropathic pain in male but not female Brain Behavior and Immunity, 117 , 51-65

Berlim L.; Gonçalves H.; de Oliveira V.; Mattoso N.; Prudente A.; Bezerra A.; Schreiner W. 01-01-2014. Syngonanthus nitens: Why it looks like spun gold Industrial Crops and Products, 52 , 597-602

Berlim L.; Gonçalves H.; de Oliveira V.; Mattoso N.; Prudente A.; Bezerra A.; Schreiner W. 01-01-2014. Syngonanthus nitens: Why it looks like spun gold Industrial Crops and Products, 52 , 597-602