The departmental mission emphasizes basic, pre-clinical and translational research with faculty utilizing state-of-the-art techniques, along with core facilities dedicated to microscopy and murine physiology.
Our researchers investigate disciplines ranging from traditional physiology & pharmacology to cardiovascular biology, chronobiology, computational biology, membrane transport, metabolic biology, and neurobiology.
There are extensive collaborations within the department, College of Medicine and beyond, including the Center for Cardiovascular Research, the Cancer Institute, and the Neuroscience Institute.
We study the pathophysiology of heart failure, as well as the signaling mechanisms related to heart, vascular, and skeletal muscle function in health and disease.
We investigate diverse aspects of chronobiology ranging from the molecular mechanisms of core circadian clock machinery to functions of circadian rhythms orchestrating temporal organization of cellular and physiological processes.
We utilize hierarchical modeling, Bayesian inference, AI-driven simulations, and large-scale data analytics to explore inter-individual heterogeneity, systems biology, pharmacometrics, and biomedical informatics.
We study the several gatekeeping processes (e.g., ion/nutrient transport) that regulate what crosses biological membranes.
We research the regulatory networks that control energy balance, nutrient metabolism, and disease susceptibility.
We study the neurobiology of stress & addiction, the effects of diet & cancer on neurodevelopment, the roles for microglia and astrocytes in synaptic function, and the mechanisms of neuronal repair.
